Fibrinogen in neurological diseases: mechanisms, imaging and therapeutics

Nature Reviews Neuroscience 19, 283 (2018). doi:10.1038/nrn.2018.13 Authors: Mark A. Petersen, Jae Kyu Ryu & Katerina Akassoglou The blood coagulation protein fibrinogen is deposited in the brain in a wide range of neurological diseases and traumatic injuries with blood–brain barrier (BBB) disruption. Recent research has uncovered pleiotropic roles for fibrinogen in the activation of CNS inflammation, induction of scar formation in the
Source: Nature Reviews Neuroscience - Category: Neuroscience Authors: Tags: Review Source Type: research