Platelet storage lesions: What more do we know now?

Platelet concentrate (PC) transfusions are a life-saving adjunct to control and prevent bleeding in cancer, haematological, surgical and trauma patients. PC availability and safety are limited by the development of platelet storage lesions (PSLs) and risk of bacterial contamination. PSLs are a series of biochemical, structural and functional changes that occur from blood collection to transfusion. Understanding of PSLs is key for devising interventions that prolong PC shelf life to improve PC access and wastage.
Source: Transfusion Medicine Reviews - Category: Hematology Authors: Source Type: research