Influence of Local Myocardial Damage on Index of Microcirculatory Resistance and Fractional Flow Reserve in Target and Nontarget Vascular Territories in a Porcine Microvascular Injury Model

Conclusions In Yorkshire swine models, local microvascular damage increased both FFR and IMR in a vessel supplying target myocardial territory. However, IMR and FFR were maintained in the other vessel. These physiological results in swine support the concept that FFR measurement might provide useful information for evaluating nonculprit lesions in clinical settings involving significant acute myocardial injury.

http://www.interventions.onlinejacc.org/cgi/content/short/11/8/717?rss=1

Source: Journal of the American College of Cardiology: Cardiovascular Interventions - April 16, 2018 Category: Cardiology Authors: Lee, J. M., Kim, H. K., Lim, K. S., Park, J.-K., Choi, K. H., Park, J., Hwang, D., Rhee, T.-M., Yang, J. H., Shin, E.-S., Nam, C.-W., Doh, J.-H., Hahn, J.-Y., Koo, B.-K., Jeong, M. H. Tags: Focus on Coronary Physiology Source Type: research