Occurrence and genetic characterization of gra6 and sag2 from toxoplasma gondii oocysts in cat feces, kunming, china.
OCCURRENCE AND GENETIC CHARACTERIZATION OF GRA6 AND SAG2 FROM TOXOPLASMA GONDII OOCYSTS IN CAT FECES, KUNMING, CHINA.
Southeast Asian J Trop Med Public Health. 2016 Nov;47(6):1134-42
Authors: Liang Y, Chen J, Meng Y, Zou F, Hu J, Esch GW
Abstract
Toxoplasma gondii-like oocysts were detected in 4% of cat feces using
light microscopy in Kunming, China. Amplicon was generated from these oocysts
using a T. gondii- but not Hammondia hammondi-specific primer set. Cat and KM
mouse were susceptible to infection by these T. gondii-like oocysts. Tissue cysts
were found in the brain of the experimentally infected animals and were infective
to mouse, indicating that the T. gondii-like oocysts isolated from naturally infected
cats had a facultative secondary host life cycle. Comparison of GRA6 and SAG2
sequences with those of reference strains indicated that the cat-derived T. gondii
(KM isolate) were typical of T. gondii genotype II. This is the first report of isolation,
identification, and genotyping of T. gondii from feline feces in China. The
occurrence of oocyst shedding in the cat population studied was higher than that
found in most cat populations world-wide, which strongly implies the need for
further studies of population genetic structure of T. gondii, as well as for prevention
and control of T. gondii infection in cats in China.
PMID: 29634160 [PubMed - in process]
Source: Southeast Asian Journal of Tropical Medicine and Public Health - Category: Tropical Medicine Tags: Southeast Asian J Trop Med Public Health Source Type: research
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