Haemophilus influenzae from patients at the largest university tertiary care center, thailand 2012 - 2015.
HAEMOPHILUS INFLUENZAE FROM PATIENTS AT THE LARGEST UNIVERSITY TERTIARY CARE CENTER, THAILAND 2012 - 2015.
Southeast Asian J Trop Med Public Health. 2017 Mar;48(2):331-7
Authors: Tribuddharat C, Pongpech P, Srifuengfung S
Abstract
Haemophilus influenzae was isolated from 556 different patients, mostly
10 years or under, at a tertiary referral hospital in Bangkok, Thailand during 2012
- 2015. Peak period of detection was from January to March. Thirty-nine percent of
the isolates were β-lactamase positive. β-Lactamase-negative ampicillin-resistant
H. influenzae (BLNAR) constituted 2% of β-lactamase-negative cases. H. influenzae
was susceptible to ampicillin (58%), amoxicillin/clavulanate (99%), cefotaxime
(100%), ceftriaxone (100%), cefuroxime (99%), ciprofloxacin (99%), chloramphenicol
(86%), tetracycline (75%), and trimethoprim-sulphamethoxazole (52%).
β-Lactamase-producing isolates (72%) showed high minimal inhibitory concentration
(MIC) to ampicillin (128-516 μg/ml) and all BLNAR isolates low ampicillin
MIC (2-16 μg/ml). These findings indicate that the level of ampicillin resistance
in H. influenzae depended on differences in resistance mechanism.
PMID: 29641884 [PubMed - in process]
Source: Southeast Asian Journal of Tropical Medicine and Public Health - Category: Tropical Medicine Tags: Southeast Asian J Trop Med Public Health Source Type: research
More News: Amoxicillin | Augmentin | Ceftriaxone | Cefuroxime | Cipro | Ciprofloxacin | Haemophilus Influenzae (Hib) | Hospitals | International Medicine & Public Health | Rocephin | Tetracycline | Thailand Health | Trimethoprim | Tropical Medicine