Prospective Cardiovascular Genetics Evaluation in Spontaneous Coronary Artery Dissection [Original Articles]

Conclusions:
In this series, 8.2% of the SCAD patients evaluated had a molecularly identifiable disorder associated with vascular disease. The most common diagnosis was vascular Ehlers–Danlos syndrome. Patients with positive gene testing were significantly younger at the time of their first SCAD event. A low threshold for genetic testing should be considered in patients with SCAD.

Source: Circulation: Cardiovascular Genetics - April 12, 2018 Category: Cardiology Authors: Kaadan, M. I., MacDonald, C., Ponzini, F., Duran, J., Newell, K., Pitler, L., Lin, A., Weinberg, I., Wood, M. J., Lindsay, M. E. Tags: Genetics, Aneurysm, Vascular Disease Original Articles Source Type: research