Evaluation of a commercial stool concentrator kit compared to direct smear and formalin-ethyl acetate concentration methods for diagnosis of parasitic infection with special reference to opisthorchis viverrini sensu lato in thailand.
In this study, we evaluated the diagnostic accuracy of a commercial
stool concentrator kit with that of a direct simple smear method and a modified
FECT. In diagnosing parasite infection and opisthorchiasis, the commercial kit
had greater sensitivity (43.8-58.5%) than direct smear method (12.5-31.7%), but
was less sensitive than FECT (73.2-75%). In a separate sample population, similar
results were obtained when comparing the diagnostic accuracy of the commercial
kit and FECT. However, the commercial kit was more effective in a field setting
than FECT, and had better accuracy than direct smear method, which suggests
that the kit could have potential utility in epidemiological studies and control
programs of opisthorchiasis, as well as other parasitic infections. The design of
the self-contained one-tube kit plus its long storage time after sample preparation
provides a considerable advantage over other methods, such as direct or Kato
thick smear method, under similar field conditions.
PMID: 29620342 [PubMed - in process]
Source: Southeast Asian Journal of Tropical Medicine and Public Health - Category: Tropical Medicine Tags: Southeast Asian J Trop Med Public Health Source Type: research