Prevalence and risk factors of hepatitis b and c virus infections among hemodialysis patients from private hemodialysis units in surabaya, indonesia.
PREVALENCE AND RISK FACTORS OF HEPATITIS B AND C VIRUS INFECTIONS AMONG HEMODIALYSIS
PATIENTS FROM PRIVATE HEMODIALYSIS UNITS IN SURABAYA, INDONESIA.
Southeast Asian J Trop Med Public Health. 2016 Sep;47(5):927-34
Authors: Utsumi T, Pranawa, Lusida MI, Yano Y, Wahyuni RM, Istimagfiroh A, Amin M, Rinonce HT, Juniastuti, Wardana A, Tjempakasari A, Basuki W, Soetjipto, Hotta H, Hayashi Y
Abstract
The aims of the present study were to profile seroprevalence of hepatitis
B virus (HBV) and hepatitis C virus (HCV) infections, and possible risk factors
among hemodialysis (HD) patients in private hemodialysis units (HDU) in Surabaya,
Indonesia. Sera were obtained from 180 HD patients in 4 different private
HDUs and tested for hepatitis B surface antigen (HBsAg) and antibody to HCV
(anti-HCV). Patients without HBsAg and anti-HCV at first sampling were followed
serologically every 3 months for 9 months, while those with HBsAg or anti-HCV
positive sera were subjected continually to PCR to detect HBV DNA and HCV
RNA. The prevalence of hepatitis infections varied widely between the HDUs,
from 0% to 8.1% of patients positive for HBsAg and 0% to 60.6% of those positive
for anti-HCV, respectively. These values were markedly higher than those among
the general population, but not as high as in governmental HDUs in Indonesia.
New incidence of HBV was not detected in any HDU, whereas that of HCV was
found in two HDUs, HCV-1b in one HDU and HCV-1a in the...
Source: Southeast Asian Journal of Tropical Medicine and Public Health - Category: Tropical Medicine Tags: Southeast Asian J Trop Med Public Health Source Type: research