Expression signature of some immunity genes triggered in Apis mellifera carpatica model by Pseudomonas entomophila experimental infection.
Expression signature of some immunity genes triggered in Apis mellifera carpatica model by Pseudomonas entomophila experimental infection.
Roum Arch Microbiol Immunol. 2016 Jan-Jun;75(1-2):18-24
Authors: Neagu A, Raþiu AC, Mihalache (Radu) MR, Lazãr V, Chifiriuc MC, Ecovoiu AA
Abstract
Herein we report the expression profiles of
certain immunity genes from Apis mellifera
carpatica worker individuals experimentally
infected with Pseudomonas entomophila L48
strain. Changes of the relative expression of
abaecin, Relish, dorsal, Toll-1, domeless, and
Duox genes were monitored by qRT-PCR. Our
results were compared with similar ones from
Drosophila melanogaster model and suggest that
these genes are involved in the anti-infective
defense mechanisms. Our study opens
investigation avenues for modern prophylactic
and therapeutic approaches of infections affecting
the honeybees, but also for identifying new
orthologous genes involved in the human innate
immune response.
PMID: 29616529 [PubMed - in process]
Source: Roumanian Archives of Microbiology and Immunology - Category: Microbiology Tags: Roum Arch Microbiol Immunol Source Type: research