Rationale and evidence for the development of a durable device-based cardiac neuromodulation therapy for hypertension

We assessed the feasibility of achieving acute, sustained blood pressure reductions through the use of cardiac pacing algorithms delivered via standard dual-chamber pacing based on introducing short atrio-ventricular (AV) delays (SAVD). Eighteen hypertensive subjects (57.3 ± 9.8 years old; 10 male and 8 female) with average initial systolic and diastolic blood pressures of 151.2 ± 17.6/92.2 ± 12.7 mmHg already scheduled to undergo an invasive electrophysiology procedure were included in this study.

Source: Journal of the American Society of Hypertension - March 22, 2018 Category: Cardiology Authors: Bing Yang, Yue Wang, Fengxiang Zhang, Weizhu Ju, Hongwu Chen, Yuval Mika, Ricardo Aviv, Steven J. Evans, Daniel Burkhoff, Jie Wang, Minglong Chen Tags: Research Article Source Type: research