Synergistic effects of resveratrol and melatonin on in vitro maturation of porcine oocytes and subsequent embryo development

Resveratrol and melatonin are known for their antioxidant properties and have various biological activities. The fact that they exhibit possible synergistic effects in phytomedicine researches suggests the use of a combination of these agents to promote porcine in vitro maturation (IVM) of oocytes. Therefore, we investigated the effects of resveratrol and/or melatonin on this process; cumulus-oocyte complexes underwent IVM culture with four different conditions (control, resveratrol, melatonin or their combination).
Source: Theriogenology - Category: Genetics & Stem Cells Authors: Source Type: research