Effect of all-trans retinoic acid treatment on prohibitin and renin-angiotensin-aldosterone system expression in hypoxia-induced renal tubular epithelial cell injury

Conclusion:
The results suggest that ATRA acts as a positive regulator of PHB1, PHB2 and ACE2, and as a negative regulator of ACE1, angiotensin I, and angiotensin II in a RTEC model system under hypoxia/reoxygenation conditions.

Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - September 11, 2014 Category: Biomedical Science Authors: Zhou, T.-B., Ou, C., Rong, L., Drummen, G. P. Tags: Articles Source Type: research