Integration of Temporal and Spatial Properties of Dynamic Connectivity Networks for Automatic Diagnosis of Brain Disease

Alzheimer ’s disease (AD) is a chronic neurodegenerative disease that usually starts slowly and gets worse over time. It is the most common cause of dementia among older adults. It is reported that AD accounts for 60 to 80 percent of dementia cases (Burns and Iliffe, 2009). In 2015, there were approximatel y 29.8 million people worldwide with AD, and causes about 1.9 million death (Vos et al., 2016). Dementia is the loss of cognitive functioning (e.g., thinking, remembering and reasoning) and behavioral abilities, which often causes a severe burden on the patient and caregiver, including social, psy chological, physical and economic elements.

Source: Medical Image Analysis - April 3, 2018 Category: Radiology Authors: Biao Jie, Mingxia Liu, Dinggang Shen Source Type: research