Non-invasive prenatal paternity testing using cell-free fetal DNA from maternal plasma: DNA isolation and genetic marker studies

In cases like sexual assault, many pregnant women want to confirm the biological father as soon as possible to decide whether to undergo elective termination of pregnancy. The conventional method for prenatal diagnosis of paternity is invasive, such as amniocentesis or chorionic villus sampling [1]. These methods have distinct disadvantages for pregnant women. Apart from the risk of serious complications such as miscarriage [2,3] or congenital malformations [4,5], the stage of pregnancy at which these methods are applicable is late, delaying the decision on pregnancy outcome.

Source: Legal Medicine - March 31, 2018 Category: Forensic Medicine Authors: Shanshan Zhang, Shuyi Han, Maoxiu Zhang, Yunshan Wang Source Type: research