Radical treatment of muscle-invasive bladder cancer —are options equal?

ConclusionsPatients with MIBC can potentially be treated with surgery, or with bladder preserving techniques —RT and CRT. No randomised evidence exists to directly compare radical options and a frequently used neoadjuvant chemotherapy regime also lacks randomised data. Patients responded well to and tolerated fractionated gemcitabine and cisplatin. This regime can be used in patients with an eGFR as low as 40 ml/min.Our results support the use of chemo-radiotherapy or surgery as radical treatments in suitable patients with MIBC. All patients should be considered for and be given the option of both cystectomy and chemo-radiotherapy.

http://link.springer.com/10.1007/s13566-018-0347-6

Source: Journal of Radiation Oncology - March 29, 2018 Category: Cancer & Oncology Source Type: research