Gadd45a knockdown alleviates oxidative stress through suppressing the p38 MAPK signaling pathway in the pathogenesis of preeclampsia

Preeclampsia (PE) is a hypertensive disease associated with vascular oxidative stress (OS). Besides, cell response to OS triggers growth arrest and DNA damage inducible alpha (Gadd45a). Herein, we investigated the effect of Gadd45a on OS in PE.

Source: Placenta - March 28, 2018 Category: Reproduction Medicine Authors: Fa-Hong Li, Na Han, Yong Wang, Qian Xu Source Type: research