Effect of phytate and zinc ions on fluoride toothpaste efficacy using an in situ caries model

Conclusions <ABS-P>Results: suggest phytate has little impact on fluoride’s ability to promote early-stage lesion remineralisation or prevent more advanced lesion demineralisation in this in situ caries model. Similarly, results suggest zinc ions do not impair fluoride efficacy. Clinical significance Toothpastes may contain therapeutic or cosmetic agents that could interfere with fluoride’s caries prevention efficacy. The present in situ caries study has demonstrated that phytate, added to provide enhanced extrinsic stain removal/prevention, and zinc, added to inhibit malodour, do not impair fluoride efficacy.
Source: Journal of Dentistry - Category: Dentistry Source Type: research