Altered grey matter volume and cortical thickness in patients with schizo-obsessive comorbidity

Schizo-obsessive comorbidity (SOC) has been proposed to delineate the subgroup of schizophrenia (SCZ) patients who also have significant obsessive-compulsive (OC) symptoms (Attademo et al., 2016; Cunill and Castells, 2011; Swets et al., 2014). In previous studies, the incidence of OC symptoms in SCZ patients has been found to be 10 times higher than the general population (Esslinger et al., 2015; Peng et al., 2014; Tonna et al., 2015). Patients with SOC are characterized by earlier onset, higher hospitalization rate (Owashi et al., 2010), more severe cognitive deficits (Cunill et al., 2013; Schirmbeck et al., 2013) and more severe psychotic symptoms (Faragian et al., 2012; Fr ías et al., 2014) compared with patients with SCZ alone.
Source: Psychiatry Research: Neuroimaging - Category: Psychiatry Authors: Source Type: research