Glycosaminoglycans and their sulfate derivatives differentially regulate the viability and gene expression of osteocyte-like cell lines

In conclusion, highly sulfated glycosaminoglycans inhibit osteocyte apoptosis in vitro and promote an osteoblast-supporting gene expression profile.

Source: Journal of Bioactive and Compatible Polymers - September 9, 2014 Category: Research Authors: Tsourdi, E., Salbach-Hirsch, J., Rauner, M., Rachner, T. D., Moller, S., Schnabelrauch, M., Scharnweber, D., Hofbauer, L. C. Tags: Original Articles Source Type: research