Sepsis: Gut bacteria induce protective IgA

Nature Reviews Drug Discovery 17, 242 (2018). doi:10.1038/nrd.2018.49 Author: Sarah Crunkhorn The mechanisms mediating serum immunoglobulin A (IgA) responses and their potential role in protective immunity remain unknown. Wilmore and colleagues show that members of the Proteobacteria phylum in the gut of mice promote a T cell-dependent increase in serum IgA and IgA-secreting bone marrow plasma
Source: Nature Reviews Drug Discovery - Category: Drugs & Pharmacology Authors: Tags: Research Highlight Source Type: research