Immunotherapy: iPSC-based cancer vaccine
Nature Reviews Drug Discovery 17, 242 (2018).
doi:10.1038/nrd.2018.48
Author: Sarah Crunkhorn
Pluripotent cells share antigens with cancer cells, suggesting that they could be used to prime the immune system to target cancer. Here, Kooreman and colleagues report the development of a vaccine based on irradiated mouse induced pluripotent stem cells. Prophylactically, the vaccine inhibited tumour growth
Source: Nature Reviews Drug Discovery - Category: Drugs & Pharmacology Authors: Sarah Crunkhorn Tags: Research Highlight Source Type: research
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