Cancer: Tipping the splicing balance to kill cancer cells
Nature Reviews Drug Discovery 17, 239 (2018).
doi:10.1038/nrd.2018.38
Author: Megan Cully
Mutations in genes encoding splicing factors are commonly found in samples from patients with several haematological cancers, as well as some solid tumours. A new paper in Nature Medicine describes a novel, orally available splicing modulator that preferentially kills cancer cells with mutations in
Source: Nature Reviews Drug Discovery - Category: Drugs & Pharmacology Authors: Megan Cully Tags: Research Highlight Source Type: research