Cancer: Tipping the splicing balance to kill cancer cells

Nature Reviews Drug Discovery 17, 239 (2018). doi:10.1038/nrd.2018.38 Author: Megan Cully Mutations in genes encoding splicing factors are commonly found in samples from patients with several haematological cancers, as well as some solid tumours. A new paper in Nature Medicine describes a novel, orally available splicing modulator that preferentially kills cancer cells with mutations in
Source: Nature Reviews Drug Discovery - Category: Drugs & Pharmacology Authors: Tags: Research Highlight Source Type: research