Peptidoglycan recognition by the innate immune system

Nature Reviews Immunology 18, 243 (2018).
doi:10.1038/nri.2017.136

Authors: Andrea J. Wolf & David M. Underhill
The innate immune system recognizes microbial products using germline-encoded receptors that initiate inflammatory responses to infection. The bacterial cell wall component peptidoglycan is a prime example of a conserved pathogen-associated molecular pattern (PAMP) for which the innate immune system has evolved sensing mechanisms. Peptidoglycan is

Source: Nature Reviews Immunology - January 2, 2018 Category: Allergy & Immunology Authors: Andrea J. Wolf David M. Underhill Tags: Review Source Type: research