Transcription regulation by the Mediator complex

Nature Reviews Molecular Cell Biology 19, 262 (2018). doi:10.1038/nrm.2017.115 Author: Julie Soutourina Alterations in the regulation of gene expression are frequently associated with developmental diseases or cancer. Transcription activation is a key phenomenon in the regulation of gene expression. In all eukaryotes, mediator of RNA polymerase II transcription (Mediator), a large complex with modular organization, is generally
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Tags: Review Source Type: research