Clinicopathologic Correlation of Choroidal Invasion in Retinoblastoma

Although choroidal invasion in retinoblastoma eyes is commonly observed pathologically, it has rarely been identified ophthalmoscopically or with ultrasound. Over a 2-year period, a 6-year-old girl was treated for bilateral retinoblastoma with systemic chemotherapy, intrarterial chemotherapy, laser, cryotherapy, and brachytherapy. She developed a dome-shaped brown/orange fundus lesion that was speckled on its surface with overlying serous retinal detachment (Fig 1A). Ultrasound confirmed that this emanated from the choroid but did not connect to the ciliary body (Fig 1B).

Source: Ophthalmology - March 19, 2018 Category: Opthalmology Authors: David H. Abramson, Robert Folberg, Jasmine H. Francis Tags: Pictures & Perspectives Source Type: research