Infraorbital Nerve Involvement on Magnetic Resonance Imaging in Igg4-Related Ophthalmic Disease: A Highly Suggestive Sign

A 47-year-old man presented to the orbital surgery department with a history of recent orbital inflammation. He  presented with bilateral orbital swelling and a palpable mass above the right eye (Fig 1A, black arrow). He had no fever and laboratory tests were normal. Coronal T2 (Fig 1B) and coronal fat-saturated post-contrast T1 weighted imaging magnetic resonance imaging (Fig 1C) showed an enlargement and e nhancement of the left infra-orbital nerve (white arrow). A biopsy was performed with histological and immunohistochemical analysis (Fig 1D) revealing a lymphoplasmacytic infiltrate expressing IgG4, confirming the diagnosis of IgG4-related ophthalmic disease.
Source: Ophthalmology - Category: Opthalmology Authors: Tags: Pictures & Perspectives Source Type: research