Prospective Study of Epigenetic Age Acceleration and Incidence of Cardiovascular Disease Outcomes in the ARIC Study (Atherosclerosis Risk in Communities) [Original Articles]

Conclusions:
In this sample of blacks, increased epigenetic age acceleration in whole blood was a potential risk marker for incident fatal coronary heart disease, peripheral arterial disease, and heart failure independently of chronological age and traditional CVD risk factors. DNA methylation–based measures of biological aging may help to identify new pathophysiological mechanisms contributing to the development of CVD.

Source: Circulation: Cardiovascular Genetics - March 19, 2018 Category: Cardiology Authors: Roetker, N. S., Pankow, J. S., Bressler, J., Morrison, A. C., Boerwinkle, E. Tags: Aging, Cardiovascular Disease, Epidemiology, Risk Factors, Epigenetics Original Articles Source Type: research