Cardiovascular risk factors predicting cardiac events are different in patients with rheumatoid arthritis, psoriatic arthritis and psoriasis

Increased cardiovascular risk in rheumatoid arthritis (RA) is well established. Examining traditional cardiovascular risk factors alone underestimates cardiovascular risk in RA. Systematic inflammation, measured by erythrocyte sedimentation rate or C-reactive protein is also a major risk factor. However, the contribution of traditional cardiovascular risk factors (such as obesity and hyperlipidaemia) compared to inflammation is uncertain in psoriatic arthritis (PsA) and RA. We examine the incidence of Major Adverse Cardiac Events (MACE) among patients with RA, PsA, psoriasis and controls adjusting for risk factors, inflammation and Disease Modifying Anti-Rheumatic Drug treatment, to better define cardiovascular risk.

Source: Seminars in Arthritis and Rheumatism - March 17, 2018 Category: Rheumatology Authors: Roxanne Cooksey, Sinead Brophy, Jonathan Kennedy, Fabiola Fernandez Gutierrez, Tim Pickles, Ruth Davies, Vincent Piguet, Ernest Choy Source Type: research