Heterogeneous Multifrequency Direct Inversion (HMDI) for Magnetic Resonance Elastography with Application to a Clinical Brain Exam

Magnetic resonance elastography (Hirsch et  al., 2016) encodes induced shear wave displacements using phase-contrast MRI imaging, enabling estimation of in vivo tissue viscoelastic properties by wave inversion. These mechanical properties, including mechanical “stiffness” and viscosity, are of strong medical interest (Mariappan et al., 2010; Sack et al., 2013), and elastography-related research is widespread. One of the strengths of MRE is that full-field displacements of tissue are acquired; however magnetic resonance elastography is challenged by complicated tissue structures and the ill-posed nature of wave inversion.

Source: Medical Image Analysis - March 17, 2018 Category: Radiology Authors: Eric Barnhill, Penny J. Davies, Cemre Ariyurek, Andreas Fehlner, J ürgen Braun, Ingolf Sack Source Type: research