Defining the Optimal Method for Reporting Prostate Cancer Grade and Tumor Extent on MR/US Fusion Targeted Biopsies

MR/ultrasound fusion targeted biopsy(TB) routinely samples multiple cores from each MR lesion of interest. Pathologists can evaluate the extent of cancer involvement and grade using an individual-core(IC) or aggregate(AG) method, which could potentially lead to differences in reporting. We reviewed patients who underwent TB followed by radical prostatectomy(RP). TB cores were evaluated for grade and tumor extent by two methods. IC method: grade for each TB lesion was based on the core with the highest Gleason score.

Source: Human Pathology - March 15, 2018 Category: Pathology Authors: Jennifer B. Gordetsky, Luciana Schultz, Kristin K. Porter, Jeffrey W. Nix, John V. Thomas, Maria del Carmen Rodriguez Pena, Soroush Rais-Bahrami Source Type: research