A77 1726 (Leflunomide) blocks and reverses cardiac hypertrophy and fibrosis in mice

In conclusion, A77 1726 attenuated cardiac hypertrophy and cardiac fibrosis via inhibiting FYN/AKT signaling pathway.

Source: Clinical Science - March 14, 2018 Category: Biomedical Science Authors: Ma, Z.-G., Zhang, X., Yuan, Y.-P., Jin, Y.-G., Li, N., Kong, C.-Y., Song, P., Tang, Q.-Z. Tags: PublishAheadOfPrint Source Type: research