In vitro characterization of MOD ‐5014, a novel long‐acting carboxy‐terminal peptide (CTP)‐modified activated FVII

ConclusionThe comparable in vitro activity of MOD‐5014 and rhFVIIa paves the way for in vivo pharmacology evaluations of MOD‐5014 in preparation for clinical studies.

Source: Haemophilia - February 1, 2018 Category: Hematology Authors: A. Bar ‐Ilan, T. Livnat, M. Hoffmann, L. Binder, M. Zakar, R. Guy, Y. Felikman, L. Moschcovich, B. Shenkman, D. Monroe, O. Hershkovitz, G. Kenet, G. Hart Tags: ORIGINAL ARTICLE Source Type: research