Glutamine ‐rich toxic proteins GrtA, GrtB, and GrtC together with the antisense RNA AsgR constitute a toxin–antitoxin‐like system in Corynebacterium glutamicum

This article is protected by copyright. All rights reserved. We report a new type I toxin‐antitoxin system in Corynebacterium glutamicum which is a workhorse of amino acid production. The TA system is composed of three repeated glutamine‐rich proteins encoded by grtABC genes and an antisense small RNA AsgR. The expression of grtABC is induced by several stressors while the repression of grtABC is achieved by the grtA‐AsgR duplex formation at the 3′ untranslated region (3′‐UTR) and subsequent degradation by RNase III.
Source: Molecular Microbiology - Category: Microbiology Authors: Tags: Research Article Source Type: research