The effect of splenectomy on the levels of PCV ‐13‐induced memory B‐ and T cells

ConclusionOur results suggest that spleen is important, but not essential, for survival and/or generation of memory IgG B cells. In contrast, it seems to be indispensable for PCV‐13‐specific memory TH1‐cell levels. Studies enhancing the levels of vaccine‐induced memory cells and further enlightening the immune responses in asplenic individuals are required to develop more effective vaccination strategies against OPSI.

Source: International Journal of Clinical Practice - February 1, 2018 Category: Internal Medicine Authors: Umut Gazi, Djursun Karasartova, Ibrahim Tayfun Sahiner, Ayse Semra Gureser, Ozgur Tosun, Mehmet Kursat Derici, Mete Dolapci, Aysegul Taylan Ozkan Tags: ORIGINAL PAPER Source Type: research