Drug safety and big clinical data: Detection of drug ‐induced anaphylactic shock events

DiscussionWe proposed an information retrieval‐based method for detecting drug‐induced anaphylaxis, by querying structured and unstructured data in a CDW. CDW queries are less specific than spontaneous reporting and Diagnosis‐related Groups queries, although their sensitivity is much higher. CDW queries can facilitate monitoring by pharmacovigilance experts. Our method could be easily incorporated in the routine practice.

Source: Journal of Evaluation in Clinical Practice - March 13, 2018 Category: General Medicine Authors: Guillaume Bouzill é, Marie‐Noëlle Osmont, Louise Triquet, Natalia Grabar, Cécile Rochefort‐Morel, Emmanuel Chazard, Elisabeth Polard, Marc Cuggia Tags: ORIGINAL ARTICLE Source Type: research