A novel PITX2 mutation in non ‐syndromic orodental anomalies

ConclusionsThis study for the first time demonstrates that the PITX2 mutation could lead to non‐syndromic orodental anomalies in humans. We propose that the specific location in the C‐terminal domain of PITX2 is exclusively necessary for tooth development.

Source: Oral Diseases - March 13, 2018 Category: ENT & OMF Authors: N Intarak, T Theerapanon, C Ittiwut, K Suphapeetiporn, T Porntaveetus, V Shotelersuk Tags: ORIGINAL ARTICLE Source Type: research