Hyperacute Monocyte Gene Response Patterns Are Associated With Lower Extremity Vein Bypass Graft Failure [Original Articles]

Conclusions:
A novel combination of dynamic gene clustering, linear models, and Bayesian network analysis has identified a core set of regulatory genes whose manipulations could migrate vein grafts toward a more favorable remodeling phenotype.

Source: Circulation: Cardiovascular Genetics - March 12, 2018 Category: Cardiology Authors: Rehfuss, J. P., DeSart, K. M., Rozowsky, J. M., OMalley, K. A., Moldawer, L. L., Baker, H. V., Wang, Y., Wu, R., Nelson, P. R., Berceli, S. A. Tags: Computational Biology, Inflammation, Functional Genomics, Revascularization, Peripheral Vascular Disease Original Articles Source Type: research