Corticofugal Circuits: Communication Lines from the Cortex to the Rest of the Brain

This article is protected by copyright. All rights reserved. Pyramidal cells in cortical layers 5 and 6 are the only cells in the cerebral cortex with axons that leave the cortex to influence the thalamus. Layer 6 cells provide modulatory feedback input to all thalamic nuclei, whereas layer 5 cells provide driving input to higher order thalamic nuclei. Here, we review current understanding of the corticofugal pathways and speculate on their functional contributions to neural processing and behavior.
Source: The Journal of Comparative Neurology - Category: Neurology Authors: Tags: Review Source Type: research