Performance of the cobas Hepatitis B virus (HBV) test using the cobas 4800 system and comparison of HBV DNA quantification ability between the COBAS AmpliPrep/COBAS TaqMan HBV test version 2.0 and cobas HBV test

Hepatitis B virus (HBV) infection is a major public health problem worldwide. Individuals with chronic HBV infection are at risk for cirrhosis, liver failure, and hepatocellular carcinoma. Treatment against HBV aims to maintain undetectable HBV DNA levels and to improve the prognosis of HBV-related liver disease. Despite advances in vaccination and treatment, the global burden of HBV remains high. Approximately 30% of the world's population shows serological evidence of a current or past HBV infection, and an estimated 257 million people were living with chronic HBV infection globally in 2015 [1,2].
Source: Journal of Clinical Virology - Category: Virology Authors: Source Type: research