Prevalence and stability of antibodies to thirteen polyomaviruses and association with cutaneous squamous cell carcinoma: A population-based study

Sun exposure is the main risk factor for cutaneous squamous cell carcinoma (cSCC), particularly in people with fair skin [1]. Organ transplant recipients on immunosuppressive therapy have considerably increased risk of cSCC [2], suggesting that viruses may also play a role. Recently several new members of the polyomavirus (PyV) family have been identified and there are indications that these may contribute to the development of cSCC [3]. The most frequently studied HPyV is Merkel cell polyomavirus (MCV), and its integration in Merkel cell carcinoma tumours is the strongest evidence for HPyV involvement in human oncogenesis [4,5].

Source: Journal of Clinical Virology - February 3, 2018 Category: Virology Authors: Annika Antonsson, Rachel E. Neale, Peter O ’Rourke, Leesa Wockner, Angelika Michel, Michael Pawlita, Tim Waterboer, Adèle C. Green Tags: Short communication Source Type: research