Varenicline reduces heavy drinking, smoking in men with both risk behaviors

Among a group of patients with alcohol use disorders who were seeking alcohol treatment, varenicline significantly reduced heavy drinking and comorbid smoking in men but not in women, a placebo‐controlled study involving 131 patients found. The gender difference could be attributed in part to lower tolerability of varenicline among women, who reduced or discontinued doses of varenicline in greater numbers than men, the researchers reported. Study results were published online Dec. 20, 2017 in JAMA Psychiatry.

http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1002%2Fpu.30310

Source: The Brown University Psychopharmacology Update - March 9, 2018 Category: Psychiatry Tags: Addiction Treatment Source Type: research