PBOV1 as a potential biomarker for more advanced prostate cancer based on protein and digital histomorphometric analysis

ConclusionsOur study demonstrates that the PBOV1 protein could be used to discriminate Grade Group 3 and above PCa. Additionally, the PBOV1 protein could be involved in modulating changes to the nuclear architecture of PCa cells. Confirmatory studies are warranted in an independent population for further validation.

Source: The Prostate - March 9, 2018 Category: Urology & Nephrology Authors: Neil M. Carleton, Guangjing Zhu, Mikhail Gorbounov, M. Craig Miller, Kenneth J. Pienta, Linda M. S. Resar, Robert W. Veltri Tags: ORIGINAL ARTICLE Source Type: research