Freshly-mixed and setting calcium-silicate cements stimulate human dental pulp cells

Direct pulp capping aims to seal the vital pulp tissue exposed by trauma or deep caries excavation, in an attempt to enable the pulp to heal and so to avoid a more invasive and often technically difficult root-canal treatment. Pulp exposure mostly involves odontoblast destruction and fibroblast injury [1,2]. A successful pulp-capping procedure requires a mild inflammatory reaction along with a supply of mainly calcium ions to stimulate recruitment and proliferation of dental pulp stem cells from their vascular niche [3,4].

Source: Dental Materials - March 7, 2018 Category: Materials Science Authors: Mariano S. Pedano, Xin Li, Shuchen Li, Zeyi Sun, Stevan M. Cokic, Eveline Putzeys, Kumiko Yoshihara, Yashuhiro Yoshida, Zhi Chen, Kirsten Van Landuyt, Bart Van Meerbeek Source Type: research