Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons

Nature Medicine 24, 313 (2018).
doi:10.1038/nm.4490

Authors: Yingxiao Shi, Shaoyu Lin, Kim A Staats, Yichen Li, Wen-Hsuan Chang, Shu-Ting Hung, Eric Hendricks, Gabriel R Linares, Yaoming Wang, Esther Y Son, Xinmei Wen, Kassandra Kisler, Brent Wilkinson, Louise Menendez, Tohru Sugawara, Phillip Woolwine, Mickey Huang, Michael J Cowan, Brandon Ge, Nicole Koutsodendris, Kaitlin P Sandor, Jacob Komberg, Vamshidhar R Vangoor, Ketharini Senthilkumar, Valerie Hennes, Carina Seah, Amy R Nelson, Tze-Yuan Cheng, Shih-Jong J Lee, Paul R August, Jason A Chen, Nicholas Wisniewski, Victor Hanson-Smith, T Grant Belgard, Alice Zhang, Marcelo Coba, Chris Grunseich, Michael E Ward, Leonard H van den Berg, R Jeroen Pasterkamp, Davide Trotti, Berislav V Zlokovic & Justin K Ichida

Source: Nature Medicine - February 5, 2018 Category: General Medicine Authors: Yingxiao Shi Shaoyu Lin Kim A Staats Yichen Li Wen-Hsuan Chang Shu-Ting Hung Eric Hendricks Gabriel R Linares Yaoming Wang Esther Y Son Xinmei Wen Kassandra Kisler Brent Wilkinson Louise Menendez Tohru Sugawara Phillip Woolwine Mickey Huang Michael J Cowa Tags: Article Source Type: research