Enhancing cancer immunotherapy using antiangiogenics: opportunities and challenges

Enhancing cancer immunotherapy using antiangiogenics: opportunities and challengesEnhancing cancer immunotherapy using antiangiogenics: opportunities and challenges, Published online: 06 March 2018; doi:10.1038/nrclinonc.2018.29The aberrant tumour vasculature and the associated angiogenic factors have been implicated in tumour immune evasion and progression. Herein, the authors provide their perspectives on how normalization of the tumour microenvironment using antiangiogenic agents could potentially increase the effectiveness of immunotherapies and improve the outcomes of patients with cancer. The authors also highlight important considerations for future research in this area.
Source: Nature Clinical Practice Oncology - Category: Cancer & Oncology Authors: Source Type: research