Functional Imaging Methods for Assessment of Minimal Residual Disease in Multiple Myeloma: Current Status and Novel ImmunoPET Based Methods

Imaging plays a key role is assessment of myeloma. Lytic bone lesions are optimally assessed using structural imaging however the structural changes lag in assessment of functional changes in the assessment of disease. Functional imaging with Fluoro Deoxy glucose (FDG) positron emission tomography computerized tomography (PET CT) is useful in assessment of high risk myeloma, provides prognostic information and is helpful in monitoring therapy response. However it is nonspecific and may not be optimal in assessing treatment response to immunotherapeutic agents.
Source: Seminars in Hematology - Category: Hematology Authors: Source Type: research