Higher levels of kallikrein ‐8 in female brain may increase the risk for alzheimer's disease

In conclusion, multiple features of AD are more pronounced in females. Here we show for the first time that this sex‐specific difference may be meditated by estrogen‐induced KLK8 overproduction long before AD pathology emerges. This article is protected by copyright. All rights reserved.

http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1111%2Fbpa.12599

Source: Brain Pathology - January 1, 2018 Category: Neurology Authors: Kathy Keyvani, Yvonne M ünster, Nirup K. Kurapati, Sebastian Rubach, Andreas Schönborn, Emre Kocakavuk, Mohamed Karout, Pia Hammesfahr, Ya‐chao Wang, Dirk M. Hermann, Sarah Teuber‐Hanselmann, Arne Herring Tags: Research Article Source Type: research