Replicative stress and alterations in cell cycle checkpoint controls following acetaminophen hepatotoxicity restrict liver regeneration

ConclusionsCell cycle lesions following mitochondrial and DNA damage led to failure of hepatic regeneration in acetaminophen toxicity but their reversibility offers molecular targets for treating acute liver failure.

Source: Cell Proliferation - February 1, 2018 Category: Cytology Authors: Preeti Viswanathan, Yogeshwar Sharma, Priya Gupta, Sanjeev Gupta Tags: ORIGINAL ARTICLE Source Type: research