Recurrent attacks of acute hepatic porphyria: major role of the chronic inflammatory response in the liver

ConclusionAltogether this study has important impacts on AIP care underlying that hemin needs to be restricted to severe neurovisceral crisis and suggests that alternative treatment targeting the liver such as ALAS1 and HO1 inhibitors, and anti‐inflammatory therapies should be considered in patients with recurrent AIP.This article is protected by copyright. All rights reserved.

Source: Journal of Internal Medicine - March 1, 2018 Category: Internal Medicine Authors: Caroline Schmitt, Hugo Lenglet, Ang èle Yu, Constance Delaby, Arndt Benecke, Thibaud Lefebvre, Philippe Letteron, Valérie Paradis, Staffan Wahlin, Sverre Sandberg, Pauline Harper, Eliane Sardh, Arne Kristian Sandvik, Johannes R. Hov, Aasne Karine Aarsan Tags: Original Source Type: research