Intra ‐operative high‐resolution mapping of slow wave propagation in the human jejunum: Feasibility and initial results

Conclusions & InferencesThis study introduces HR mapping of human intestinal slow waves, and provides first descriptions of intestinal pacemaker sites and velocity anisotropy. Future translation to other intestinal regions, disease states, and postsurgical dysmotility holds potential for improving the basic and clinical understanding of small intestine pathophysiology. This study evaluated the feasibility of high‐resolution (HR) slow wave mapping in the human small intestine, including defining spatiotemporal propagation patterns. Slow wave frequency, amplitude, downstroke width, and anisotropic velocity profile were quantitatively defined, and focal pacemakers and disordered propagation events were mapped. This study presents the first account of human HR intestinal mapping, offering a technique for quantitative assessment of intestinal bioelectrical activity and enabling future investigation of potential slow wave abnormalities in human diseases and/or postsurgical dysmotility.
Source: Neurogastroenterology and Motility - Category: Gastroenterology Authors: Tags: ORIGINAL ARTICLE Source Type: research